5-a]pyrimidine相关论文
吡唑并嘧啶是一类具有广泛生物活性的杂环结构母体,同时,氮芥类药物被广泛应用于临床治疗癌症.本文基于药物设计的拼合原理,以简单......
Discovery of [1,2,4]triazolo[1,5-a]pyrimidine derivatives as new bromodomain-containing protein 4 (B
Targeting bromodomain-containing protein 4 (BRD4) has been proved to be an effective strategy for cancer therapy. To dat......
The isoindolinone and biaryl scaffolds are prevalent in natural products and drug molecules, which have showed broad and......
Synthesis, Crystal and Biological Activity of 3-(2,4-Difluorobenzyl)-5-(p-tolyl)-7-(trifluoromethyl)
The title compound 3-(2,4-difluorobenzyl)-5-(p-tolyl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin2-amine (6) was synthes......
Cyclocondensation Reations of 3-Amino-l,2,4-triazole with 3-(Benzyl idene)-6-fl uoro-th iochroman-4-
为探究吕家坨井田地质构造格局,根据钻孔勘探资料,采用分形理论和趋势面分析方法,研究了井田7......
Facile Syntheses of New Pyrazolo[1,5-a] pyrimidines Derivatives via Reactions of Enaminones with Ami
为探究吕家坨井田地质构造格局,根据钻孔勘探资料,采用分形理论和趋势面分析方法,研究了井田7......
Synthesis and Crystal Structure of Ethyl 2-Methylthio-7-phenylpyrazolo[1,5-a]pyrimidine-3-carboxylat
The crystal structure of ethyl 2-methylthio-7-phenylpyrazolo[l,5-a]pyrimidine-3-carboxylate (C16H15N3O2S, Mr = 313.37) h......
Synthesis, Structure and Biological Activities of 2-Methylthio-3-cyano-7-(4-methoxyphenyl)-pyrazolo[
The crystal structure of 2-methylthio-3-cyano-7-(4-methoxyphenyl)-pyrazolo[1,5- a]-pyrimidine (C15H12N4OS, Mr = 296.35) ......
设计并合成了七个2-{[5-（取代吡唑-5-基）-1，3，4-噁二唑-2-基]甲巯基）-5，7-二甲基-1，2,4-三唑[1，5-a]嘧啶类化合物，均为未见文献报道的新化合......
Synthesis of 5,7-Dimethyl-2-(5-Substituted-1,3,4-Oxadiazole-2-yl)- Methylenethio-1,2,4-Triazolo[1,5-
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Synthesis, Structure and Biological Activities of 2-Methylthio-3-cyano-7-（4-methoxyphenyl）- pyrazolo
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以2-巯基-5，7-二甲基-1，2，4-三唑并[1，5-a]嘧啶为原料，设计合成了17种含5，7-二甲基-1，2，4-三唑并[1，5-a]嘧啶环和1,2，4-三唑环的新型双杂环化......
Synthesis and Crystal Structure of Ethyl 2- Methylthio-7-phenylpyrazolo[1,5-a] pyrimidine-3-carboxyl
The crystal structure of ethyl 2-methylthio-7-phenylpyrazolo[l,5-a]pyrimidine-3-carboxylate (C16H15N3O2S, Mr = 313.37) h......
The title compound, C16n14N4S, has been synthesized by the reaction of pentane-2,4-dione with 5-amino-3-benzylthio-4-cya......
